AI Target Discovery

Rank the targets that belong on your bench

Assaygrove reads your omics and the literature the way a computational biologist would, then tells you which ten targets are worth a wet-lab program.

Target Rankings 8 targets scored
# Target Score Evidence
1 KRAS
0.91
Tier 1 View
2 MAPK3
0.87
Tier 1 View
3 PIK3CA
0.82
Tier 1 View
4 EGFR
0.74
Tier 2 View
5 AKT1
0.68
Tier 2 View
6 PTEN
0.61
Tier 2 View
7 CDK4
0.44
Tier 3 View
8 MDM2
0.38
Tier 3 View
18 months
average time lost on a failed indication target
7 in 10
targets fail first wet-lab validation
$400K
median bench spend on a target that never validates

Figures from published biotech failure analyses and industry post-mortem reviews

Target selection is where most programs fail silently

In published post-mortems of failed drug programs, the root cause is rarely chemistry or formulation. It is a target that was prioritized before the evidence was properly integrated. A target that looked compelling in one dataset and was never cross-referenced against the full omics picture.

The problem is not that research teams lack the skills. It is that the process of integrating omics data, literature signals, and genetic evidence into a coherent ranked list takes months of focused computational biology work. Most teams do not have the bandwidth to do that rigorously for every candidate before committing bench time.

How It Works

Three steps to a defensible target list

01

Connect

Upload or connect omics datasets: bulk RNA-seq expression matrices, proteomics data, GWAS summary statistics. Standard file formats. No PHI required.

02

Rank

Multi-evidence scoring integrates your omics signals against 40M+ indexed literature records, genetic associations, and functional evidence. Each target receives a composite confidence score with a decomposable breakdown.

03

Decide

Receive a ranked target list with per-target evidence cards: genetic evidence tier, functional support, literature confidence, and a recommended priority action. Export to CSV or JSON.

What research teams are seeing

"We ran our oncology target shortlist through Assaygrove during our early-access pilot. The ranking surfaced a target we had deprioritized based on a single dataset. The multi-omics view changed our decision. That program is now in active validation."

Dr. Lena Baumann Senior Computational Biologist, oncology-focused biotech Early-access cohort

"The evidence card decomposition is what sold me. Not a black-box score, but three separate evidence components I could interrogate. As a VP Research, I need to defend prioritization decisions to the board. This gave me the language to do that."

Marcus Chan VP Research, CNS-focused drug discovery startup Early-access pilot
6 of 8

Early-access research teams reprioritized away from their initial lead target based on Assaygrove ranking

From our early-access program, Q3 2025

A full evidence breakdown for every target

Each ranked target comes with a decomposable evidence card. Not a single confidence number. Three scored components: genetic evidence (GWAS hits, eQTLs, rare variant burden), functional evidence (knockout phenotypes, protein interactions), and literature evidence (publication density, recency weighting, entity confidence).

Recommended priority action tells you exactly what the evidence supports: Prioritize, Monitor, or Deprioritize, with the specific tier driving the call.

Genetic evidence: strongest causal prior
Functional evidence: mechanism support
Literature evidence: community confidence signal
MAPK3 Prioritize
Genetic
0.88
Functional
0.79
Literature
0.65
Genetic Evidence

Strong GWAS association in colorectal carcinoma (p = 3.2e-12). eQTL signal in colon tissue. Rare variant burden in familial CRC cohort.

Functional Evidence
  • CRISPR knockout reduces proliferation in 3 cell lines
  • 17 high-confidence protein interaction partners
Literature
147 indexed records 12 high-confidence

Commit bench time to the targets that deserve it

A rigorous ranked target list, built the way a computational biologist builds it, available in hours rather than months.

Boston-based team, founded 2024. Independently funded.